Azilsartan Impurity 52 CAS 1449029-77-9
| CAS No. | 1449029-77-9 |
| Molecular Formula | C29H26N4O7 |
| Molecular Weight | 542.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Azilsartan Impurity 52 (CAS 1449029-77-9), a pharmacopoeial impurity reference standard (molecular formula C29H26N4O7, MW 542.54 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Azilsartan Impurity 52 (C29H26N4O7) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Azilsartan Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C29H26N4O7 |
| Molecular Weight | 542.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 4 |
Related Azilsartan Standards
- Azilsartan Impurity 100 (CAS CATO-C4X-1096100)
- Azilsartan Impurity 55 (CAS 1883681-10-4)
- Azilsartan Impurity 57 (CAS 3031851-96-1)
- Azilsartan Impurity 162 (CAS CATO-C4X-1096162)
- Azilsartan Impurity 33 (CAS 1417576-00-1)
- Azilsartan Impurity 183 (CAS CATO-C4X-1096183)
- Azilsartan impurity 147 (CAS CATO-C4X-1096147)
- Azilsartan Impurity 138 (CAS CATO-C4X-1096138)
Recommended Standards
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- Olmesartan Impurity 55 (CAS 1227626-44-9)
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- 3-(4-Ethyl-1H-imidazol-5-yl)pyridine (CAS 473693-15-1)
- 1-(Tetrahydrofuran-3-yl)ethan-1-amine hydrochloride (CAS 1803592-17-7)
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- 2-(2-Formyl-6-methylpyridin-4-yl)acetic acid (CAS 1393583-69-1)
- 3-Amino-4-methyl-2,3-dihydro-1h-indol-2-one hydrochloride (CAS 1214103-58-8)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
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