1-(Tetrahydrofuran-3-yl)piperazinetrifluoroacetic acid salt 1449117-43-4 CAS 1449117-43-4
| CAS No. | 1449117-43-4 |
| Molecular Formula | C8H16N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Tetrahydrofuran-3-yl)piperazinetrifluoroacetic acid salt 1449117-43-4 (CAS 1449117-43-4) is a high-purity analytical reference standard with the molecular formula C8H16N2OC2HF3O2 and a molecular weight of 270.25 g/mol.
The molecular framework of 1-(Tetrahydrofuran-3-yl)piperazinetrifluoroacetic acid salt 1449117-43-4 (C8H16N2OC2HF3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H16N2O C2HF3O2 |
| Molecular Weight | 270.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Tetrahydrofuran Standards
- Benzyl (tetrahydrofuran-3-yl)carbamate (CAS 100390-87-2)
- 1-Methyl-3-(((tetrahydrofuran-2-yl)methyl)carbamoyl)-1h-pyrazole-4-carboxylic acid (CAS 1006440-66-9)
- (Tetrahydrofuran-2-yl)methyl 2-(3-oxopiperazin-2-yl)acetate (CAS 1008015-25-5)
- (R)-2-(Tetrahydrofuran-3-yl)-1,3,6,2-dioxazaborocane (CAS 100858-40-0)
- 1-(Tetrahydrofuran-2-carbonyl)piperidin-4-one (CAS 1016505-60-4)
- 2-Methyl-4-((tetrahydrofuran-2-yl)methoxy)benzenesulfonyl chloride (CAS 1016534-67-0)
- 5-Methyl-2-((tetrahydrofuran-2-yl)methoxy)benzenesulfonyl chloride (CAS 1016712-73-4)
- 2-(((Tetrahydrofuran-2-yl)methyl)thio)propanoic acid (CAS 1016754-61-2)
Recommended Standards
- ((2-Chloroethyl)amino)(oxo)methanesulfonic acid (CAS 785006-00-0)
- ETHYL 2-(DIMETHYLAMINO)-2-(THIOPHEN-2-YL)ACETATE (CAS 1007885-50-8)
- Tert-butyl octahydro-2,7-naphthyridine-2(1H)-carboxylate hydrochloride (CAS 2387602-43-7)
- (R)-6-Methyl-4,7-diazaspiro[2.5]octane dihydrochloride (CAS 1199792-91-0)
- 1-(5-fluoropyridin-2-yl)ethan-1-one (CAS 915720-54-6)
- 4-Chloro-8-isobutylpteridin-7(8H)-one (CAS 1774901-23-3)
- Isopropyl 5-bromopicolinate (CAS 1289268-91-2)
- 1,4-β - D-glucosamine - D-N-acetylglucosamine HCl (CAS 104584-15-8（free base）)
- Labetalol Impurity 9 (CAS 22374-89-6)
- Integrin Binding Peptide trifluoroacetate salt (CAS 278792-07-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com