2-Bromo-5-chlorotoluene CAS 14495-51-3
| CAS No. | 14495-51-3 |
| Molecular Formula | C7H6BrCl |
| Molecular Weight | 205.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-chlorotoluene.
2-Bromo-5-chlorotoluene (CAS 14495-51-3), molecular formula C7H6BrCl and molecular weight 205.48 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-5-chlorotoluene (C7H6BrCl) is characterized by chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-5-chlorotoluene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6BrCl |
| Molecular Weight | 205.48 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl/Br-containing |
Related Bromo Standards
- 2-Bromo-1-chloro-3-methylbenzene (CAS 69190-56-3)
- 2-Bromo-1-chloro-4-methyl-benzene (CAS 57310-39-1)
- 2-Bromo-4-chlorotoluene (CAS 27139-97-5)
- 2-Bromo-6-chlorotoluene (CAS 62356-27-8)
- 1-Bromo-2-chloro-3-methylbenzene (CAS 97329-43-6)
- 3-Bromo-5-chlorotoluene (CAS 329944-72-1)
- 4-Bromo-2-chlorotoluene (CAS 89794-02-5)
- 4-Bromo-3-chlorotoluene (CAS 6627-51-6)
Recommended Standards
- Vildagliptin Impurity 71 (CAS 3974-99-0)
- (2S,5S)-Methyl 5-methylpyrrolidine-2-carboxylate (CAS 97373-38-1)
- 1,2,4-Trichloro-5-ethynylbenzene (CAS 6546-87-8)
- 1,2,3-Trichloro-5-ethynylbenzene (CAS 2013531-87-6)
- 4-Amino-8-methylthiochroman 1,1-dioxide (CAS 1184534-31-3)
- 2-Cyclobutyl-7-iodo-3H-imidazo[4,5-b]pyridine (CAS 1125745-29-0)
- tert-Butyl 3-((chlorosulfonyl)methyl)azetidine-1-carboxylate (CAS 1934928-22-9)
- 4-bromo-3-(bromomethyl)isoquinoline (CAS 193013-88-6)
- Ethyl 3-oxo-6-phenyl-2,3,4,5-tetrahydropyridazine-4-carboxylate (CAS 94011-50-4)
- Trans-O-Coumaric Acid (CAS 614-60-8)
- N-(2-((5-Chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide (CAS 1191911-27-9)
- N-{4-[4-(4-fluorophenyl)piperazin-1-yl]phenyl}acetamide (CAS 303151-18-0)
- (3,5-Bis(dimethylamino)-1H-1,2,4-triazol-1-yl)(p-tolyl)methanone (CAS 478032-05-2)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
Why CATO?
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