7-fluoro-2-hydroxy-pyrido[1,2-a]pyrimidin-4-one CAS 1449598-85-9
| CAS No. | 1449598-85-9 |
| Molecular Formula | C8H13FN2O2 |
| Molecular Weight | 188.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-fluoro-2-hydroxy-pyrido[1,2-a]pyrimidin-4-one (C8H13FN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
7-fluoro-2-hydroxy-pyrido[1,2-a]pyrimidin-4-one (CAS 1449598-85-9), molecular formula C8H13FN2O2 and molecular weight 188.20 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13FN2O2 |
| Molecular Weight | 188.20 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 6-Amino-2-methylpyridine-3-sulfonic acid (CAS 1399663-63-8)
- 5-fluorobenzofuran-3-carboxylic acid (CAS 147373-09-9)
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- 5-Methoxypyridine-3-sulfonamide (CAS 1553088-23-5)
- (3-Bromo-2-methylpyridin-4-yl)boronic acid (CAS 2096338-89-3)
- 2-Methoxy-N-(5-methyl-4-(p-tolyl)thiazol-2-yl)acetamide (CAS 691397-09-8)
- 5-(Hydroxymethyl)-3,3-dimethylpyrrolidin-2-one (CAS 133390-85-9)
- BUtyl[(2-nitrophenyl)methyl]amine (CAS 777002-11-6)
- 1-[4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pent-4-en-1-one (CAS 2377606-47-6)
- 5-(Thiophen-2-yl)furan-2-carbaldehyde (CAS 32364-30-0)
- 3-Hydroxy-2-(methylsulfonamido)benzenesulfonamide (CAS 1243476-55-2)
- 1-(4-Chlorophenyl)-5-oxopyrrolidine-3-carbonyl chloride (CAS 930781-56-9)
- Brivaracetam Impurity 207 (CAS CATO-C4X-2007207)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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