5′-Bromo-2′-hydroxyacetophenone CAS 1450-75-5
| CAS No. | 1450-75-5 |
| Molecular Formula | C8H13BrO2 |
| Molecular Weight | 221.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5′-Bromo-2′-hydroxyacetophenone (CAS 1450-75-5), a certified reference material (molecular formula C8H13BrO2, MW 221.09 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, 5′-Bromo-2′-hydroxyacetophenone is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 221.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5′-Bromo-2′-hydroxyacetophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13BrO2 |
| Molecular Weight | 221.09 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
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- 5-Bromo-2-fluoro-4-methyl-benzenethiol (CAS 108404-38-2)
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Recommended Standards
- 1-Bromo-3-(1-ethynylcyclopropyl)benzene (CAS 1379308-96-9)
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- (3-Bromo-5-fluorophenyl)methanethiol (CAS 1510308-55-0)
- Methyl 2-(3-fluoro-4-(trifluoromethyl)phenyl)acetate (CAS 300355-64-0)
- ethyl 2-cyclopentyl-2-hydroxyacetate (CAS 33487-24-0)
- (2S,3S)-2-(1-phenyl-1H-pyrazol-4-yl)tetrahydrofuran-3-carboxylic acid (CAS 1820579-51-8)
- Piperacillin Impurity 91 (CAS CATO-C4X-173291)
- Sodium 6-methylpyridine-3-sulfinate (CAS 1138034-14-6)
- (R)-2-(3-Oxocyclopentyl)acetonitrile (CAS 909564-94-9)
- 3-Chloro-N-(2-fluorobenzyl)propanamide (CAS 895367-68-7)
- TLR7-agonist-1 (CAS 1642857-69-9)
- N-(4-(tert-butyl)phenyl)-4,6-dimethoxy-1,3,5-triazin-2-amine (CAS 303046-81-3)
- Semaglutide impurity 28 (CAS CATO-C4X-222628)
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