3-(1,3,4-Thiadiazol-2-yl)propanoic acid CAS 14501-20-3
| CAS No. | 14501-20-3 |
| Molecular Formula | C5H6N2O2S |
| Molecular Weight | 158.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(1,3,4-Thiadiazol-2-yl)propanoic acid (CAS 14501-20-3), molecular formula C5H6N2O2S and molecular weight 158.18 g/mol, is a CATO reference standard with documented purity and traceability.
3-(1,3,4-Thiadiazol-2-yl)propanoic acid (C5H6N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(1,3,4-Thiadiazol-2-yl)propanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6N2O2S |
| Molecular Weight | 158.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Thiadiazol Standards
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Recommended Standards
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- 3-(4-Bromo-1h-pyrazol-1-yl)propanoic acid (CAS 925146-35-6)
- 2-Chloro-3-(oxiran-2-ylmethoxy)pyridine (CAS 152560-63-9)
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