4-Methyl-3-propoxy-1H-1,2,4-triazol-5(4H)-one CAS 145027-96-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Methyl-3-propoxy-1H-1,2,4-triazol-5(4H)-one.

CATO supplies 4-Methyl-3-propoxy-1H-1,2,4-triazol-5(4H)-one (CAS 145027-96-9), a certified reference material (molecular formula C6H11N3O2, MW 157.17 g/mol) for analytical method development and quality control.

The molecular framework of 4-Methyl-3-propoxy-1H-1,2,4-triazol-5(4H)-one (C6H11N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Methyl-3-propoxy-1H-1,2,4-triazol-5(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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