Apremilast Impurity 41 CAS 1450657-31-4
| CAS No. | 1450657-31-4 |
| Molecular Formula | C12H17NO4S |
| Molecular Weight | 271.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Apremilast Impurity 41 (CAS 1450657-31-4) is a certified pharmaceutical impurity reference standard with the molecular formula C12H17NO4S and a molecular weight of 271.33 g/mol.
The molecular framework of Apremilast Impurity 41 (C12H17NO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Apremilast Impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17NO4S |
| Molecular Weight | 271.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Apremilast Standards
- Apremilast Impurity 81 (CAS CATO-C4X-100981)
- Apremilast Impurity 131 (CAS CATO-C4X-1009131)
- Apremilast Impurity 48 (CAS 1450657-28-9)
- Apremilast impurity 14 (CAS 253168-94-4)
- Apremilast Impurity 25 (CAS 608142-27-4)
- Apremilast Impurity 55 (CAS 885268-06-4)
- Apremilast Impurity 73 (CAS CATO-C4X-100973)
- Apremilast Impurity 74 (CAS CATO-C4X-100974)
Recommended Standards
- 10R-1126 383148-77-4 [(1E)-1,2,3,4-tetrahydronaphthalen-1-ylidene]amino thiophene-2-carboxylate (CAS 383148-77-4)
- Tosyl-D-valine (CAS 68005-71-0)
- Blonanserin Impurity 17 (CAS 132812-72-7)
- tert-Butyl(phenylsulfonyl)glycinate (CAS 34545-74-9)
- S-Adenosyl-L-Methionine Impurity 32 (CAS CATO-C4X-138132)
- Rosuvastatin EP Impurity H Sodium Salt (CAS 1335110-44-5 (free acid))
- Upadacitinib Impurity 112 (CAS CATO-C4X-2405112)
- 4217-66-7 2-Phenyl-1,2-propanediol DL-2-Phenylpropane-1,2-diol 1,2-Propanediol, 2-phenyl- AI3-13060 EINECS 224-154-5 (+-)-1-Methyl-1-phenyl-1,2-ethanediol (+-)-2-Phenyl-1,2-propanediol (CAS 4217-66-7)
- 2-((1-Ethyl-2,5-dioxopyrrolidin-3-yl)thio)benzoic acid (CAS 350030-47-6)
- (Z)-3-Amino-3-phenyl-acrylic acid ethyl ester (CAS 53256-19-2)
- 2-Cycloheptylethanamine Hydrochloride (CAS 1187930-98-8)
- tert-Butyl (5-chloropyridin-3-yl)carbamate (CAS 342603-15-0)
- 2-Mercapto-5-(morpholinomethyl)pyrimidin-4-ol (CAS 89665-74-7)
- Des-Gly34-Tirzepatide (CAS CATO-CPTD788940)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com