8-Hydroxyquinoline-4-carbaldehyde CAS 14510-07-7
| CAS No. | 14510-07-7 |
| Molecular Formula | C10H7NO2 |
| Molecular Weight | 173.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 173.17 g/mol gives 8-Hydroxyquinoline-4-carbaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Hydroxyquinoline-4-carbaldehyde (CAS 14510-07-7), molecular formula C10H7NO2 and molecular weight 173.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Hydroxyquinoline-4-carbaldehyde (C10H7NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-Hydroxyquinoline-4-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7NO2 |
| Molecular Weight | 173.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Hydroxyquinoline Standards
- 2-Hydroxyquinoline-7-carbaldehyde (CAS 1260762-89-7)
- 4-Hydroxyquinoline-7-carboxaldehyde (CAS 1261490-52-1)
- 6-Hydroxyquinoline-4-carbaldehyde (CAS 1261490-63-4)
- 7-Hydroxyquinoline-5-carbaldehyde (CAS 1261544-80-2)
- 3-Hydroxyquinoline-6-carbaldehyde (CAS 1261626-85-0)
- 4-Hydroxyquinoline-2-carbaldehyde (CAS 168141-99-9)
- 4-Hydroxyquinoline-3-carboxaldehyde (CAS 7509-12-8)
- 4-Hydroxyquinoline-6-carboxaldehyde (CAS 916812-25-4)
Recommended Standards
- alpha-Cyanocinnamic Acid (CAS 14378-06-4)
- 5-Isopropyl-2-oxo-1,3-oxazolidine-4-carboxylic acid (CAS 1468529-36-3)
- 4-(Pyridin-4-yl)-1,3,5-triazin-2-amine (CAS 143261-63-6)
- Ethyl 5-(hydroxymethyl)-4,5-dihydro-1,2-oxazole-3-carboxylate (CAS 147008-07-9)
- 2,3-Dihydro-1H-pyrrolizine-7-carbonitrile (CAS 67421-67-4)
- ethyl 3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylate (CAS 187222-16-8)
- (3S,4R)-3-Fluoro-4-methoxypiperidine (CAS 2140267-29-2)
- Methyl 2-amino-4,4,4-trifluorobutanoate (CAS 188010-09-5)
- 2,2-Bis(4-hydroxy-3-methylphenyl)propane (CAS 79-97-0)
- 4-(Difluoromethyl)-6-iodo-5-nitropyridin-2-ol (CAS 1805447-71-5)
- Ethyl 2-oxo-2-((3,4,5-trifluorophenyl)thio)acetate (CAS 1443309-70-3)
- Azetidin-3-yl(4-cyclobutylpiperazin-1-yl)methanone (CAS 1238877-84-3)
- Sodium 3-(difluoromethoxy)benzoate (CAS 1017528-43-6)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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