Methyl 10-bromo-9-fluoro-6,7-dihydro-5H-5,7-methanobenzo[c]imidazo[1,2-a]azepine-2-carboxylate CAS 1451085-27-0
| CAS No. | 1451085-27-0 |
| Molecular Formula | C15H12BrFN2O2 |
| Molecular Weight | 351.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 10-bromo-9-fluoro-6,7-dihydro-5H-5,7-methanobenzo[c]imidazo[1,2-a]azepine-2-carboxylate (CAS 1451085-27-0), molecular formula C15H12BrFN2O2 and molecular weight 351.17 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, Methyl 10-bromo-9-fluoro-6,7-dihydro-5H-5,7-methanobenzo[c]imidazo[1,2-a]azepine-2-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 351.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Methyl 10-bromo-9-fluoro-6,7-dihydro-5H-5,7-methanobenzo[c]imidazo[1,2-a]azepine-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H12BrFN2O2 |
| Molecular Weight | 351.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Methyl 2-amino-4-(3-methoxyphenyl)pyrimidine-5-carboxylate (CAS 1187385-80-3)
- 1-(1,2-Oxazol-5-yl)propan-2-one (CAS 115706-48-4)
- 1-Bromo-5-fluoro-3-methoxy-2-nitrobenzene (CAS 1805593-21-8)
- (oxan-2-yl)methanesulfonyl chloride (CAS 187164-16-5)
- 2-Chlorobenzothioamide (CAS 15717-17-6)
- 2-Bromo-4-cyano-6-(difluoromethyl)pyridine-3-sulfonamide (CAS 1804912-20-6)
- Darolutamide Impurity 51 (CAS CATO-C4X-310651)
- Ilaprazole Impurity 211 (CAS CATO-C4X-1130211)
- Des-Ala21-Tirzepatide (CAS CATO-CPTD788952)
Why CATO?
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