2-Fluoro-5-isopropoxypyridine-3-boronic acid CAS 1451391-01-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1451391-01-7
Molecular FormulaC8H11BFNO3
Molecular Weight198.99 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-5-isopropoxypyridine-3-boronic acid CAS 1451391-01-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Fluoro-5-isopropoxypyridine-3-boronic acid.

2-Fluoro-5-isopropoxypyridine-3-boronic acid (CAS 1451391-01-7) is a high-purity analytical reference standard with the molecular formula C8H11BFNO3 and a molecular weight of 198.99 g/mol.

The molecular framework of 2-Fluoro-5-isopropoxypyridine-3-boronic acid (C8H11BFNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H11BFNO3
Molecular Weight198.99 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms1

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