4-(Trifluoromethoxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline CAS 1451391-22-2
| CAS No. | 1451391-22-2 |
| Molecular Formula | C13H17BF3NO3 |
| Molecular Weight | 303.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Trifluoromethoxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline.
CATO supplies 4-(Trifluoromethoxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 1451391-22-2), a certified reference material (molecular formula C13H17BF3NO3, MW 303.09 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(Trifluoromethoxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 303.09 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17BF3NO3 |
| Molecular Weight | 303.09 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- 2-TRIFLUOROMETHOXY-4-IODIOANILINE 4-IODO-2-(TRIFLUOROMETHOXY)ANILINE 4-IODO-2-TRIFLUOROMETHOXY-PHENYLAMINE 4-Iodo-2-trifluoromethoxyaniline 874814-75-2 AS00429 BUTTPARK 83\07-28 (CAS 874814-75-2)
- 2-{5-Oxo-4-[4-(trifluoromethoxy)phenyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetic acid (CAS 860612-21-1)
- 2-({[3-(trifluoromethoxy)phenyl]methyl}carbamoyl)cyclopropane-1-carboxylic acid (CAS 1024144-58-8)
- 2-((1-(4-(Trifluoromethoxy)phenyl)-1H-pyrrol-2-yl)methylene)malononitrile (CAS 260788-89-4)
- 2-((1-(4-(Trifluoromethoxy)phenyl)-1H-pyrrol-3-yl)methylene)malononitrile (CAS 439094-26-5)
- 2-(2-(4-(Trifluoromethoxy)phenyl)thiazol-5-yl)acetic acid (CAS 1010918-95-2)
- {2-[4-(Trifluoromethoxy)phenyl]-1,3-thiazol-4-yl}acetic acid (CAS 1092330-87-4)
- 4-Methyl-2-(4-(trifluoromethoxy)phenyl)thiazole-5-carboxylic acid (CAS 187998-69-2)
Recommended Standards
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(2,2,2-trifluoroethoxy)pyridine (CAS 1416724-47-4)
- (3-Fluoro-5-((4-methoxybenzyl)carbamoyl)phenyl)boronic acid (CAS 1704082-30-3)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2,2,2-trifluoroethoxy)pyridine (CAS 1415748-20-7)
- 1-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridin-2(1H)-one (CAS 1706753-51-6)
- 4-Methyl-8,8a-dihydropyrrolo[1,2-d][1,2,4]triazine-1,6(2H,7H)-dione (CAS 182482-39-9)
- Dihydro-1-(2-methoxyethyl)-2-thioxo-4,6(1H,5H)-pyrimidinedione (CAS 560995-25-7)
- ethyl 2-methylcyclopent-1-ene-1-carboxylate (CAS 64229-84-1)
- 4-Cyclopropoxy-3-(dimethylamino)benzonitrile (CAS 1243410-98-1)
- (4-(1-Aminoethyl)phenyl)boronic acid (CAS 1258948-01-4)
- Methyl 4-hydroxy-6-(trifluoromethyl)picolinate (CAS 1060810-76-5)
- 3,6-Bis(hexylthio)phthalonitrile (CAS 344453-43-6)
- Methyl 2-Methoxy-4-methylbenzoate (CAS 81245-24-1)
- 1187165-21-4 2-Methyl-4-(4-pentyloxybenzoyl)pyridine MFCD13153312 (CAS 1187165-21-4)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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