3-(Hydroxymethyl)-5-methylphenylboronic Acid CAS 1451391-46-0
| CAS No. | 1451391-46-0 |
| Molecular Formula | C8H11BO3 |
| Molecular Weight | 165.98 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-(Hydroxymethyl)-5-methylphenylboronic Acid (CAS 1451391-46-0), a certified reference material (molecular formula C8H11BO3, MW 165.98 g/mol) for analytical method development and quality control.
The molecular framework of 3-(Hydroxymethyl)-5-methylphenylboronic Acid (C8H11BO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11BO3 |
| Molecular Weight | 165.98 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
Related Hydroxymethyl Standards
- (4-(Hydroxymethyl)-3-methylphenyl)boronic acid (CAS 1218790-88-5)
- (2-(Hydroxymethyl)-4-methylphenyl)boronic acid (CAS 1451391-52-8)
- (4-(Hydroxymethyl)-2-methylphenyl)boronic acid (CAS 166386-66-9)
- 3-(Hydroxymethyl)-2-methylphenylboronic acid (CAS 2121514-26-7)
- 5-(Hydroxymethyl)-2-methylphenylboronic Acid (CAS 631909-12-1)
- 4-(Hydroxymethyl)-3-(Trifluoromethyl)pyrazole (CAS 1001020-13-8)
- 4-(Hydroxymethyl)-2-methoxy-1,2-oxaphospholane 2-oxide (CAS 633278-49-6)
- 6-(Hydroxymethyl)furo[2,3-d]pyridazin-7(6H)-one (CAS 18270-75-2)
Recommended Standards
- 3-(Methoxymethyl)phenylboronic Acid (CAS 142273-84-5)
- (2-Hydroxy-4,6-dimethylphenyl)boronic acid (CAS 1421935-36-5)
- (3-Ethyl-2-hydroxyphenyl)boronic acid (CAS 1462329-57-2)
- (3-Methoxy-2-methylphenyl)boronic acid (CAS 1313617-76-3)
- 3-Chloro-5-(cyclopropylmethoxy)pyridazine (CAS 1346691-28-8)
- Methyl 3-bromobenzo[a]azulene-10-carboxylate (CAS 2765731-96-0)
- 4-(Boc-Amino)-1-isopentylpiperidine (CAS 888944-67-0)
- 3-(4-Hydroxyphenyl)-4-oxo-4H-chromen-7-yl hydrogen sulfate (CAS 688025-49-2)
- 2-((2-Ethoxyphenyl)amino)propanamide (CAS 1096160-22-3)
- Silicic acid (CAS 10279-57-9)
- 2-Phenylquinazoline-4(1H)-thione (CAS 6483-99-4)
- Tert-butyl 4-(6-amino-5-methylpyridin-3-yl)piperidine-1-carboxylate (CAS 1947415-48-6)
- Methyl 6-(3-fluoro-5-hydroxyphenyl)nicotinate (CAS 1417792-34-7)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
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