4-Bromo-5-chloro-2-methylphenylboronic acid CAS 1451391-48-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1451391-48-2
Molecular FormulaC7H7BBrClO2
Molecular Weight249.30 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Bromo-5-chloro-2-methylphenylboronic acid CAS 1451391-48-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 249.30 g/mol gives 4-Bromo-5-chloro-2-methylphenylboronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Bromo-5-chloro-2-methylphenylboronic acid (CAS 1451391-48-2), molecular formula C7H7BBrClO2 and molecular weight 249.30 g/mol, is a CATO reference standard with documented purity and traceability.

4-Bromo-5-chloro-2-methylphenylboronic acid (C7H7BBrClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Bromo-5-chloro-2-methylphenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H7BBrClO2
Molecular Weight249.30 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1992
Halogen ContentCl/Br-containing

Related Bromo Standards

Recommended Standards

Why CATO?