2-Chloro-6-fluoro-3-(methoxymethoxy)phenylboronic acid CAS 1451392-26-9
| CAS No. | 1451392-26-9 |
| Molecular Formula | C8H9BClFO4 |
| Molecular Weight | 234.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-6-fluoro-3-(methoxymethoxy)phenylboronic acid (CAS 1451392-26-9) is a high-purity analytical reference standard with the molecular formula C8H9BClFO4 and a molecular weight of 234.42 g/mol.
The molecular framework of 2-Chloro-6-fluoro-3-(methoxymethoxy)phenylboronic acid (C8H9BClFO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-6-fluoro-3-(methoxymethoxy)phenylboronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9BClFO4 |
| Molecular Weight | 234.42 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-Chloro-5-fluoro-4-(methoxymethoxy)phenylboronic acid (CAS 1451392-28-1)
- (3-Chloro-[2,2'-bipyridin]-5-yl)boronic acid (CAS 2225170-44-3)
- (3-Chloro-[2,3'-bipyridin]-5-yl)boronic acid (CAS 2225175-36-8)
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- (3-Chloro-5-(pyrazin-2-yl)phenyl)boronic acid (CAS 2225177-93-3)
- (4-Chloro-2-phenylpyrimidin-5-yl)boronic acid (CAS 2225169-73-1)
- 1-Chloro-2-(2-iodoethoxy)ethane (CAS 42070-18-8)
- (2-Chloro-4-(methylsulfonyl)phenyl)boronic acid (CAS 1262662-38-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com