8-Isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-ol CAS 1453187-13-7
| CAS No. | 1453187-13-7 |
| Molecular Formula | C14H21N5O2 |
| Molecular Weight | 291.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-Isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-ol (CAS 1453187-13-7) is a high-purity analytical reference standard with the molecular formula C14H21N5O2 and a molecular weight of 291.35 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, 8-Isopropyl-2-((1-methylpiperidin-4-yl)oxy)pyrazolo[1,5-a][1,3,5]triazin-4-ol is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H21N5O2 |
| Molecular Weight | 291.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 5 |
Related Isopropyl Standards
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Recommended Standards
- 2-((Benzo[d]thiazol-2-ylthio)methyl)-5-hydroxy-4H-pyran-4-one (CAS 144882-20-2)
- 4-(Diethoxymethyl)-1-(4-methoxybenzyl)-1H-1,2,3-triazole (CAS 1494137-73-3)
- 1-Propanone, 2-methyl-1-(4-methyl-1-piperazinyl)-2-(4-nitrophenyl)- (CAS 1432130-38-5)
- Tert-butyl (2-((4-cyano-5,6-dimethylpyridazin-3-yl)amino)ethyl)carbamate (CAS 1427999-48-1)
- tert-Butyl 2-methyl-3-(octylamino)propanoate (CAS 1221343-02-7)
- 6-Benzylcyclohex-3-ene-1-carboxylic acid (CAS 77634-77-6)
- 2-Bromo-1H,1H-perfluorodec-1-ene (CAS 51249-65-1)
- (4-Fluoro-1H-indol-5-yl)methanamine (CAS 1368115-49-4)
- Loxoprofen impurity 89 (CAS CATO-C4X-148889)
- 2-(((Benzyloxy)carbonyl)amino)-4-(trifluoromethyl)benzoic acid (CAS 1509080-46-9)
- 2,2,2-Trifluoro-1-(5-iodo-7-(trifluoromethyl)-3,4-dihydroisoquinolin-2(1H)-yl)ethanone (CAS 625126-88-7)
- 5-Bromo-2-ethylpyridine (CAS 38749-90-5)
- 6-Fluoro-3,4-dihydro-2H-1-benzopyran-4-carboxylic acid (CAS 76301-93-4)
- C-Peptide（dog） (CAS 39016-05-2)
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