2,2,2-Trifluoro-N-(4-fluorophenyl)acetimidoyl chloride CAS 145372-30-1
| CAS No. | 145372-30-1 |
| Molecular Formula | C8H4ClF4N |
| Molecular Weight | 225.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2,2,2-Trifluoro-N-(4-fluorophenyl)acetimidoyl chloride (CAS 145372-30-1), a certified reference material (molecular formula C8H4ClF4N, MW 225.57 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 2,2,2-Trifluoro-N-(4-fluorophenyl)acetimidoyl chloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 225.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 2,2,2-Trifluoro-N-(4-fluorophenyl)acetimidoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4ClF4N |
| Molecular Weight | 225.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Chloro-2,2-difluoro-N-(3-fluoropyrazin-2-yl)acetamide (CAS 1206524-55-1)
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- 3-Methyl-4-nitro-1-(2,2,2-trifluoroethyl)-1H-pyrazole-5-carboxamide (CAS 89239-86-1)
- n-((1,3-Dimethyl-1h-pyrazol-4-yl)methyl)-3-(trifluoromethyl)aniline (CAS 1006336-83-9)
- VApreotide (acetate) (CAS 849479-74-9)
- 2-Oxo-4-(trifluoromethyl)-2,5,6,7-tetrahydro-1H-cyclopenta[b]pyridine-3-carbonitrile (CAS 371967-27-0)
- 2-{[1-methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl]oxy}-1-(morpholin-4-yl)ethan-1-one (CAS 477711-97-0)
- N-benzylpyrimidin-5-amine (CAS 104479-78-9)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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