8-Bromo-2-chloro-3-methylquinazolin-4(3H)-one CAS 1453799-86-4
| CAS No. | 1453799-86-4 |
| Molecular Formula | C9H6BrClN2O |
| Molecular Weight | 273.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 8-Bromo-2-chloro-3-methylquinazolin-4(3H)-one (C9H6BrClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 8-Bromo-2-chloro-3-methylquinazolin-4(3H)-one (CAS 1453799-86-4), a certified reference material (molecular formula C9H6BrClN2O, MW 273.51 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Bromo-2-chloro-3-methylquinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H6BrClN2O |
| Molecular Weight | 273.51 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 1-(5-Bromo-4-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone (CAS 1427504-73-1)
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- 7-Bromo-2-chloro-3-methylquinazolin-4(3H)-one (CAS 1404480-64-3)
- 5-(5-Bromo-2-chlorophenyl)isoxazol-3-amine (CAS 1480051-19-1)
- (1S,5R)-1-Phenyl-3-oxabicyclo[3.1.0]hexan-2-one (CAS 96847-53-9)
- 3-(Benzyloxy)benzo[b]thiophene-2-carbonitrile (CAS 860785-78-0)
- Ethyl 1,5-Dimethyl-1H-1,2,4-triazole-3-carboxylate (CAS 1034197-35-7)
- 2,3’-dimethylbiphenyl (CAS 611-43-8)
- 7-Acetyl-5-methyl-[1,2,4]triazolo[4,3-a]quinoxaline-1,4(2H,5H)-dione (CAS 90042-20-9)
- 1-Bromodecane-d2 (CAS 81576-60-5)
- N-1-,N-1-Diallyl-2-chloro-1,4-benzenediamine (CAS 1219957-06-8)
- 4-(Dimethylamino)pyridinium chlorochromate (CAS 81121-61-1)
- 6-(3-ethoxyphenyl)pyridin-2-amine (CAS 1125416-16-1)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
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