(E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine (2R,3R)-2,3-dihydroxysuccinate CAS 1453868-32-0
| CAS No. | 1453868-32-0 |
| Molecular Formula | C21H25N7 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine (2R,3R)-2,3-dihydroxysuccinate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine (2R,3R)-2,3-dihydroxysuccinate (CAS 1453868-32-0), molecular formula C21H25N7C4H6O6 and molecular weight 525.57 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine (2R,3R)-2,3-dihydroxysuccinate (C21H25N7C4H6O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 525.57 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (E)-N-(5-Methyl-1H-pyrazol-3-yl)-6-(4-methylpiperazin-1-yl)-2-styrylpyrimidin-4-amine (2R,3R)-2,3-dihydroxysuccinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H25N7 C4H6O6 |
| Molecular Weight | 525.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 7 |
Recommended Standards
- 6-Amino-5-(difluoromethyl)-2-hydroxypyridine-3-sulfonamide (CAS 1805213-17-5)
- (2R,5R)-2,5-Dimethylpiperazine (CAS 155836-53-6)
- 2-(Trifluoromethyl)quinoline-5-carboxylic acid (CAS 1260671-21-3)
- Methyl 4-bromo-3-methyl-5-nitrobenzoate (CAS 412944-46-8)
- A,a,1-trimethyl-1h-imidazole-2-acetic acid (CAS 865157-15-9)
- Gliclazide Impurity 2 (Methyl Tosylcarbamate) (CAS 14437-03-7)
- N-(cyanomethyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide (CAS 847868-60-4)
- 6-Bromo-N-methylbenzo[d]thiazol-2-amine (CAS 75104-92-6)
- (R)-2-((5-(3-Methyl-1H-indazol-5-yl)pyridin-3-yl)amino)-2-phenylacetamide (CAS 1613639-20-5)
- Tirzepatide Impurity 59 (CAS CATO-C4X-324059)
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