4-Amino-3-mercaptobenzoic acid CAS 14543-45-4

Purity 97%+In StockPharmaceutical Standards
CAS No.14543-45-4
Molecular FormulaC7H7NO2S
Molecular Weight169.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-Amino-3-mercaptobenzoic acid CAS 14543-45-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 169.20 g/mol gives 4-Amino-3-mercaptobenzoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-Amino-3-mercaptobenzoic acid (CAS 14543-45-4) is a high-purity analytical reference standard with the molecular formula C7H7NO2S and a molecular weight of 169.20 g/mol.

The molecular framework of 4-Amino-3-mercaptobenzoic acid (C7H7NO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-Amino-3-mercaptobenzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H7NO2S
Molecular Weight169.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Nitrogen Atoms1
Sulfur Atoms1

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