4-[3-(Trifluoromethyl)phenyl]butanoic acid CAS 145485-43-4

Purity 97%+In StockPharmaceutical Standards
CAS No.145485-43-4
Molecular FormulaC11H11F3O2
Molecular Weight232.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-[3-(Trifluoromethyl)phenyl]butanoic acid CAS 145485-43-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 232.20 g/mol gives 4-[3-(Trifluoromethyl)phenyl]butanoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-[3-(Trifluoromethyl)phenyl]butanoic acid (CAS 145485-43-4), molecular formula C11H11F3O2 and molecular weight 232.20 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 4-[3-(Trifluoromethyl)phenyl]butanoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 232.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H11F3O2
Molecular Weight232.20 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentF-containing

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Why CATO?