4-(2-Aminophenyl)butanoic acid CAS 145486-67-5
| CAS No. | 145486-67-5 |
| Molecular Formula | C10H13NO2 |
| Molecular Weight | 179.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 179.22 g/mol gives 4-(2-Aminophenyl)butanoic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-(2-Aminophenyl)butanoic acid (CAS 145486-67-5), a certified reference material (molecular formula C10H13NO2, MW 179.22 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2-Aminophenyl)butanoic acid (C10H13NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13NO2 |
| Molecular Weight | 179.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Related Aminophenyl Standards
- 3-(4-aminophenyl)-2-methylpropanoic acid (CAS 103096-03-3)
- 1-(2-Aminophenyl)-3,3-dimethylurea (CAS 1146290-34-7)
- (S)-2-(4-aminophenyl)butanoic acid (CAS 1159497-16-1)
- 2-((4-Aminophenyl)(methyl)amino)acetamide (CAS 140142-32-1)
- 1-(3-aminophenyl)-1,3-dimethylurea (CAS 1545161-09-8)
- 1-(4-Aminophenyl)-1,3-dimethylurea (CAS 1556187-74-6)
- 4-(3-Aminophenyl)butanoic acid (CAS 161466-30-4)
- 1-(3-aminophenyl)-3,3-dimethylurea (CAS 39938-79-9)
Recommended Standards
- 3-Aminopropanoic acid benzyl ester (CAS 14529-00-1)
- Methyl 3-methyl-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylate (CAS 145696-35-1)
- Methyl 3-isopropylisonicotinate (CAS 1448777-20-5)
- (dicyclopropyl-4H-1,2,4-triazol-3-yl)methanol (CAS 1461707-62-9)
- 4-((1H-pyrrol-1-yl)methyl)aniline (CAS 107484-33-3)
- 2-((4-Allyl-5-propyl-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 1416344-13-2)
- 2-(Azetidin-1-ylsulfonyl)ethan-1-amine (CAS 1157025-04-1)
- N-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylhydrazine-1-carbonyl)-5-methyl-1H-pyrazole-4-carboxamide (CAS 306978-25-6)
- (R)-N,2-Dihydroxypropanimidamide (CAS 1609388-33-1)
- 1539266-13-1 25I-NBF (hydrochloride) (CAS 1539266-13-1)
- [(4-Bromophenyl)methyl](2-methylpropyl)amine (CAS 347406-07-9)
- 4-Bromo-N-(1-methylpiperidin-4-yl)benzamide (CAS 210643-94-0)
- (S)-(2,2-Dimethyl-1,3-dioxan-4-yl)methanol (CAS 85287-64-5)
- (Glu1)-Fibrinopeptide B (human) (CAS 103213-49-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com