2-(tert-Butoxycarbonylamino)-4-fluoro-4-methylpentanoic acid CAS 1454914-50-1
| CAS No. | 1454914-50-1 |
| Molecular Formula | C11H20FNO4 |
| Molecular Weight | 249.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(tert-Butoxycarbonylamino)-4-fluoro-4-methylpentanoic acid (C11H20FNO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(tert-Butoxycarbonylamino)-4-fluoro-4-methylpentanoic acid (CAS 1454914-50-1), molecular formula C11H20FNO4 and molecular weight 249.28 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H20FNO4 |
| Molecular Weight | 249.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 3-(tert-Butoxycarbonylamino)tetrahydrothiophene-3-carboxylic acid (CAS 108329-86-8)
- 2-(tert-Butoxycarbonylamino)-5-methyl-benzoic acid (CAS 669713-60-4)
- 2-tert-Butoxycarbonylamino-2-methylpropionic acid chloromethyl ester (CAS 150109-48-1)
- 4-((tert-butoxycarbonylamino)methyl)picolinic acid (CAS 260970-57-8)
- 3-[1-(tert-butoxycarbonylamino)cyclopentyl]prop-2-ynoic acid (CAS 2305255-33-6)
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Recommended Standards
- (S)-2-((tert-Butoxycarbonyl)amino)-4-fluoro-3,3-dimethylbutanoic acid (CAS 1447941-20-9)
- 6'-Fluoro-1'-methyl-1'H-spiro[piperidine-3,2'-quinazolin]-4'(3'H)-one (CAS 1707372-68-6)
- (R)-2-((tert-Butoxycarbonyl)amino)-4-fluoro-4-methylpentanoic acid (CAS 1447616-06-9)
- Ethyl 5-((ethylsulfonyl)methyl)-4,5-dihydroisoxazole-3-carboxylate (CAS 1707403-05-1)
- (2-Methyl-1H-benzo[d]imidazol-4-yl)methanol (CAS 115577-32-7)
- Methyl 3',5'-dimethyl-[1,1'-biphenyl]-4-carboxylate (CAS 1075754-39-0)
- Dimethyl(4-(trifluoromethyl)phenyl)phosphine oxide (CAS 1333230-26-4)
- 3-((1,4,5,6-Tetrahydropyrimidin-2-yl)amino)thietane 1,1-dioxide (CAS 1854356-66-3)
- 2,2'-Dichloro diphenyl disulfide (CAS 31121-19-4)
- 2-(7-Nitro-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)ethyl 4-iodobenzoate (CAS 860786-20-5)
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- Cyclopiazonic acid (CAS 83136-88-3)
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