7-Chloro-2-(trifluoromethyl)quinazolin-4-amine CAS 1455925-72-0
| CAS No. | 1455925-72-0 |
| Molecular Formula | C9H5ClF3N3 |
| Molecular Weight | 247.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C9H5ClF3N3, 7-Chloro-2-(trifluoromethyl)quinazolin-4-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 247.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 7-Chloro-2-(trifluoromethyl)quinazolin-4-amine (CAS 1455925-72-0), a certified reference material (molecular formula C9H5ClF3N3, MW 247.60 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5ClF3N3 |
| Molecular Weight | 247.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 8-Chloro-5-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-44-5)
- 8-Chloro-6-(trifluoromethyl)quinolin-4-ol (CAS 1065092-49-0)
- 6-Chloro-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1065092-54-7)
- 5-Chloro-8-(trifluoromethyl)quinolin-4-ol (CAS 1065092-56-9)
- 1-(4-Chloro-1H-indol-3-yl)-2,2,2-trifluoro-ethanone (CAS 1119282-66-4)
- 2-Chloro-6-(5-trifluoromethylpyrazol-1-yl)pyridine (CAS 1150164-45-6)
- 2-Chloro-5-(4-(trifluoromethyl)phenyl)oxazole (CAS 1238893-96-3)
- 3-Chloro-2-(2H-pyrazol-3-yl)-5-trifluoromethyl-pyridine (CAS 1269361-42-3)
Recommended Standards
- 1-(5-Chloro-3-indolyl)-2,2,2-trifluoroethanone (CAS 1419517-55-7)
- 6-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline (CAS 18706-21-3)
- 2-Chloro-8-(trifluoromethoxy)quinoline (CAS 1352443-51-6)
- 8-Chloro-4-hydroxy-2-(trifluoromethyl)quinoline (CAS 18706-22-4)
- 4-Hydroxyquinoline-3-carboxaldehyde (CAS 7509-12-8)
- 6-methyl-octahydro-2H-pyrido[4,3-b]morpholine (CAS 1505803-80-4)
- 1-(4-Chloro-2-pyridinyl)-1-pentanone (CAS 896139-38-1)
- 6-Ethyl-2-(4-(N-methyl-N-phenylsulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide (CAS 449767-75-3)
- 6-Fluoro-3-azabicyclo[3.1.0]Hexane (CAS 2168859-46-7)
- (5-((1H-1,2,4-Triazol-1-yl)methyl)-1H-1,2,4-triazol-3-yl)(3-methoxyphenyl)methanamine (CAS 1707585-85-0)
- Lithium 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate (CAS 480450-83-7)
- 1-Amino-2-bromo-4-((4-methoxyphenyl)amino)anthracene-9,10-dione (CAS 76382-24-6)
- 1857-30-3 Securinan-11-one, (7beta,9beta)- (7beta,9beta)securinan-11-one (CAS 1857-30-3)
- Acetyl Tripeptide-1 (CAS 350595-76-5)
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