EThyl (2E)-3-(5-bromopyridin-3-yl)prop-2-enoate CAS 145743-88-0
| CAS No. | 145743-88-0 |
| Molecular Formula | C10H10BrNO2 |
| Molecular Weight | 256.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 256.10 g/mol gives EThyl (2E)-3-(5-bromopyridin-3-yl)prop-2-enoate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
EThyl (2E)-3-(5-bromopyridin-3-yl)prop-2-enoate (CAS 145743-88-0), molecular formula C10H10BrNO2 and molecular weight 256.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of EThyl (2E)-3-(5-bromopyridin-3-yl)prop-2-enoate (C10H10BrNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), EThyl (2E)-3-(5-bromopyridin-3-yl)prop-2-enoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10BrNO2 |
| Molecular Weight | 256.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 5-Bromo-1-isopropyl-1H-pyrazolo[3,4-b]pyridin-6(7H)-one (CAS 1437432-39-7)
- 4-(4-Bromophenyl)-4-methyloxazolidin-2-one (CAS 1478482-06-2)
- 3-Bromo-7-methoxy-5,6-dimethylpyrazolo-[1,5-a]pyrimidine (CAS 1429309-31-8)
- 4-(3-Bromophenyl)-4-methyl-2-oxazolidinone (CAS 1479298-59-3)
- (5,9-Dioxaspiro[3.5]Nonan-7-yl)methanol (CAS 913696-30-7)
- Furfurylamphetamine (CAS 23656-74-8)
- 2-[(1-methyl-1h-imidazol-2-yl)sulfanyl]acetic acid (CAS 71370-42-8)
- (2-Bromo-6-methoxypyridin-4-yl)methanamine (CAS 1393547-66-4)
- Dimethyl 2-(pyrrolidin-1-yl)succinate (CAS 62626-92-0)
- (2S,3R,4S)-4-Hydroxyisoleucine (CAS 55399-93-4)
- 1-methylbenzimidazole (CAS 1632-83-3)
- 2,3-Dichloropyridine (CAS 2402-77-9)
- 1-(6-Ethoxypyrimidin-4-yl)piperidin-4-ol (CAS 1065484-28-7)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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