3,4-Difluorobenzene-1-sulfonyl chloride CAS 145758-05-0
| CAS No. | 145758-05-0 |
| Molecular Formula | C6H3ClF2O2S |
| Molecular Weight | 212.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3,4-Difluorobenzene-1-sulfonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3,4-Difluorobenzene-1-sulfonyl chloride (CAS 145758-05-0) is a high-purity analytical reference standard with the molecular formula C6H3ClF2O2S and a molecular weight of 212.60 g/mol.
3,4-Difluorobenzene-1-sulfonyl chloride (C6H3ClF2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H3ClF2O2S |
| Molecular Weight | 212.60 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Difluorobenzene Standards
- 2,4-Difluorobenzene-1-sulfonyl chloride (CAS 13918-92-8)
- 2,5-Difluorobenzene-1-sulfonyl chloride (CAS 26120-86-5)
- 3,5-Difluorobenzene-1-sulfonyl chloride (CAS 210532-25-5)
- 2,3-difluorobenzene-1-sulfonyl chloride (CAS 210532-24-4)
- 3,5-difluorobenzene-1-sulfonyl fluoride (CAS 115650-77-6)
- 62094-86-4 2,5-Difluorobenzene-1-sulfonyl fluoride DTXSID80557204 (CAS 62094-86-4)
- 2,3-Difluorobenzene-1-sulfonamide (CAS 1133122-99-2)
- 2,5-Difluorobenzene-1-carbothioamide (CAS 1029623-72-0)
Recommended Standards
- 1-(5-Chloro-6-fluorobenzofuran-2-yl)ethan-1-one (CAS 2756972-08-2)
- Methyl 3-(4-chloro-2-fluorophenyl)propiolate (CAS 1339691-51-8)
- 2-Fluoro-5-chlorobenzenesulfonyl fluoride (CAS 128564-59-0)
- 2,6-Difluorobenzenesulfonyl chloride (CAS 60230-36-6)
- 3,4-Dihydro-2H-benzo[b][1,4]thiazine-6-carboxylic acid (CAS 226259-31-0)
- 4-Bromo-5-(bromomethyl)isoxazol-3(2H)-one (CAS 83014-82-8)
- rel-(1R,2R)-2-Phenylcyclopropane-1-carbaldehyde (CAS 34271-31-3)
- tert-Butyl (R)-3-chloropiperidine-1-carboxylate (CAS 1353995-32-0)
- tert-butyl 4-methyl-3,5-dioxo-2-azabicyclo[2.2.2]octane-2-carboxylate (CAS 2007920-45-6)
- 3-(5-Mercapto-4-(6-methylheptan-2-yl)-4h-1,2,4-triazol-3-yl)-n-(2-methoxyphenyl)benzenesulfonamide (CAS 748777-76-6)
- (S)-1-(3-(trifluoromethoxy)phenyl)propan-1-amine (CAS 1213107-89-1)
- Methyl 2-(2-chlorobenzamido)-5-((2,5-dimethylphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335407-55-1)
- m-PEG24-alcohol (CAS 2376450-73-4)
- Acetyl-(Leu28ยท31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com