Methyl 2-(4-fluoro-2-methylphenyl)-2-((2,2,2-trifluoroethyl)amino)acetate CAS 1457920-56-7
| CAS No. | 1457920-56-7 |
| Molecular Formula | C12H13F4NO2 |
| Molecular Weight | 279.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 279.23 g/mol gives Methyl 2-(4-fluoro-2-methylphenyl)-2-((2,2,2-trifluoroethyl)amino)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 2-(4-fluoro-2-methylphenyl)-2-((2,2,2-trifluoroethyl)amino)acetate (CAS 1457920-56-7), a certified reference material (molecular formula C12H13F4NO2, MW 279.23 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Methyl 2-(4-fluoro-2-methylphenyl)-2-((2,2,2-trifluoroethyl)amino)acetate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 279.23 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13F4NO2 |
| Molecular Weight | 279.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Ethyl 4-fluoro-2-nitro-5-(1-pyrazolyl)benzoate (CAS 1256633-41-6)
- Ethyl 5-fluoro-1-(4-nitrophenyl)-1H-pyrazole-4-carboxylate (CAS 1269291-84-0)
- Ethyl 5-fluoro-1-(2-nitrophenyl)-1H-pyrazole-4-carboxylate (CAS 1269292-33-2)
- 5-{[(2-Fluoro-4-methylphenyl)amino]methylene}-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 1379811-57-0)
- 5-fluoro-2-nitrophenyl 2-fluorobenzoate (CAS 219689-89-1)
- 1-Ethyl-4-((2-fluoro-4-nitrophenoxy)methyl)-3-methyl-1H-pyrazole (CAS 1260379-21-2)
- 5-Fluoro-3-(1-phenyl-1H-pyrazol-4-yl)benzo[d]isoxazole (CAS 651728-00-6)
- 5-Fluoro-3-(4-nitrobenzoyl)pyrimidine-2,4(1H,3H)-dione (CAS 61251-78-3)
Recommended Standards
- 1-(4-Fluorophenyl)-2-(trifluoromethyl)-1H-indole (CAS 1233881-86-1)
- N-Benzyl-2-(2,2,3,3-tetrafluoropropoxy)acetamide (CAS 402939-52-0)
- 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-amine (CAS 1218790-22-7)
- Methyl 1-(3,4-difluorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxylate (CAS 1001414-50-1)
- 2-(4-Fluoro-phenyl)-4,4-dimethoxy-1-[4-(4-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-butan-1-one (CAS 1227268-99-6)
- 406-00-8 Benzenamine, 4-fluoro-N-hydroxy- 4-Fluoro-N-hydroxybenzenamine (CAS 406-00-8)
- 2-Chloro-4-(diethylamino)pyrido[3,2-d]pyrimidine (CAS 35691-12-4)
- Agomelatine Impurity 53 (CAS CATO-C4X-110853)
- 1-(tert-Butyl) 4-methyl 4-allylpiperidine-1,4-dicarboxylate (CAS 441774-09-0)
- Methyl 2-chloro-1H-indole-3-carboxylate (CAS 152812-42-5)
- 1-Methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 113100-53-1)
- 2-(7-(2H-Naphtho[1,2-d][1,2,3]triazol-2-yl)quinolin-3-yl)benzo[d]oxazole (CAS 64887-44-1)
- 2-((Benzyloxy)carbonyl)-5-(tert-butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrole-3a(1H)-carboxylic acid (CAS 1823494-74-1)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com