Cefditoren Impurity 3 CAS 145904-68-3
| CAS No. | 145904-68-3 |
| Molecular Formula | C19H18N6O5S3 |
| Molecular Weight | 506.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Cefditoren Impurity 3 (CAS 145904-68-3, C19H18N6O5S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Cefditoren Impurity 3 (C19H18N6O5S3) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cefditoren Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18N6O5S3 |
| Molecular Weight | 506.58 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 3 |
Related Cefditoren Standards
- Cefditoren (CAS 104145-95-1)
- Cefditoren Impurity 18 (CAS CATO-C4X-135818)
- Cefditoren Impurity 32 (CAS CATO-C4X-135832)
- Cefditoren Impurity 60 (CAS CATO-C4X-135860)
- Cefditoren-d3 (CAS 2747915-67-7)
- Cefditoren Impurity 31 (CAS CATO-C4X-135831)
- Cefditoren Impurity 62 (CAS CATO-C4X-135862)
- Cefditoren Impurity 51 (CAS CATO-C4X-135851)
Recommended Standards
- TEST (CAS CATO-C3D-5869)
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- (r)-3-(2-Nitrophenoxy)pyrrolidine hydrochloride (CAS 1286207-33-7)
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- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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