tert-Butyl (E)-3-(5-bromopyridin-2-yl)acrylate CAS 1459254-51-3
| CAS No. | 1459254-51-3 |
| Molecular Formula | C12H14BrNO2 |
| Molecular Weight | 284.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl (E)-3-(5-bromopyridin-2-yl)acrylate.
CATO supplies tert-Butyl (E)-3-(5-bromopyridin-2-yl)acrylate (CAS 1459254-51-3), a certified reference material (molecular formula C12H14BrNO2, MW 284.15 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, tert-Butyl (E)-3-(5-bromopyridin-2-yl)acrylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), tert-Butyl (E)-3-(5-bromopyridin-2-yl)acrylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14BrNO2 |
| Molecular Weight | 284.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 5-(5-Bromo-2-methoxyphenoxy)pentanenitrile (CAS 1443343-41-6)
- 1-(3-((4-Bromophenoxy)methyl)azetidin-1-yl)ethanone (CAS 1467060-05-4)
- Methyl 7-bromo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carboxylate (CAS 1424984-68-8)
- Methyl 3-(4-bromophenyl)pyrrolidine-1-carboxylate (CAS 1467060-19-0)
- 4-Fluoro-5-iodo-2-methoxybenzoic acid (CAS 1171824-18-2)
- 2-Chloro-1-methyl-4-nitro-1H-imidazole (CAS 63634-21-9)
- H-Val-Asn-OH (CAS 66170-00-1)
- Methyl (2-bromo-4-formyl-6-methoxyphenoxy)acetate (CAS 676485-01-1)
- Famotidine Impurity 38 (CAS 24423-98-1)
- 6-(Chloromethyl)-N2-(2,4-dichlorophenyl)-1,3,5-triazine-2,4-diamine (CAS 1379811-37-6)
- 2-(Butyryloxy)-N,N,N-trimethylethan-1-aminium perchlorate (CAS 20292-68-6)
- 2-Methyloctanoic acid (CAS 3004-93-1)
- 5-(3-(2-Fluorophenyl)-1,2,4-oxadiazol-5-yl)pyridin-2-ol (CAS 1239843-29-8)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com