2-(Hydroxymethyl)-5-methoxypyrimidine CAS 1459748-95-8
| CAS No. | 1459748-95-8 |
| Molecular Formula | C7H12N2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(Hydroxymethyl)-5-methoxypyrimidine (CAS 1459748-95-8), a certified reference material (molecular formula C7H12N2O3C5H6N2O, MW 282.30 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Hydroxymethyl)-5-methoxypyrimidine (C7H12N2O3C5H6N2O) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-(Hydroxymethyl)-5-methoxypyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H12N2O3 C5H6N2O |
| Molecular Weight | 282.30 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 4 |
Related Hydroxymethyl Standards
- (Hydroxymethyl)urea (CAS 1000-82-4)
- 1-(5-(Hydroxymethyl)furan-2-yl)-9H-pyrido[3,4-b]indole-3-carboxylic acid (CAS 100041-05-2)
- 2-(2-(Hydroxymethyl)-4,5-dimethoxyphenyl)acetaldehyde (CAS 100059-18-5)
- 4-(Hydroxymethyl)-3-(Trifluoromethyl)pyrazole (CAS 1001020-13-8)
- 4-(Hydroxymethyl)-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one (CAS 10013-09-9)
- Methyl 1-(hydroxymethyl)-1h-pyrazole-3-carboxylate (CAS 1001519-16-9)
- 1-(Hydroxymethyl)-1h-pyrazole-3-carboxylic acid (CAS 100219-61-2)
- Ethyl 2-(hydroxymethyl)acrylate (CAS 10029-04-6)
Recommended Standards
- 2,4-Dibromo-3,5,6-trimethylaniline (CAS 857595-61-0)
- (R)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(di-2-furylphosphine) (CAS 145214-57-9)
- 2-Amino-3-fluoro-3-methylbutan-1-ol (CAS 202521-89-9)
- 2-(3-Fluoro-5-(pentafluoro-λ6-sulfanyl)phenyl)acetonitrile (CAS 1240257-90-2)
- 3-(dimethylsulfamoyl)propanoic acid (CAS 933735-41-2)
- N-Nitroso Ziprasidone EP Impurity A (CAS CATO-C4X-124054)
- 6-[2-Chloro-4-(methylthio)phenyl]-6-oxohexanoic acid (CAS 951889-94-4)
- 3-(2-Chloro-4-fluorobenzyl)piperidin-3-ol (CAS 1482374-15-1)
- 1-(4-(tert-Butyl)phenyl)-3-(2-cyclohexyl-2-hydroxyethyl)urea (CAS 1351620-88-6)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
Why CATO?
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