2,5-Dichloro-4-methylthiophene-3-sulfonyl chloride CAS 145980-83-2
| CAS No. | 145980-83-2 |
| Molecular Formula | C5H3Cl3O2S2 |
| Molecular Weight | 265.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,5-Dichloro-4-methylthiophene-3-sulfonyl chloride (CAS 145980-83-2), molecular formula C5H3Cl3O2S2 and molecular weight 265.57 g/mol, is a CATO reference standard with documented purity and traceability.
2,5-Dichloro-4-methylthiophene-3-sulfonyl chloride (C5H3Cl3O2S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H3Cl3O2S2 |
| Molecular Weight | 265.57 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
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- Acetyl-Tau Peptide (244-274) (Repeat 1 Domain) trifluoroacetate salt (CAS 2022956-56-3)
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