8-hydroxy-4-(2-hydroxyacetyl)-1H-isochromen-1-one CAS 146-04-3
| CAS No. | 146-04-3 |
| Molecular Formula | C11H8O5 |
| Molecular Weight | 220.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-hydroxy-4-(2-hydroxyacetyl)-1H-isochromen-1-one (CAS 146-04-3), molecular formula C11H8O5 and molecular weight 220.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, 8-hydroxy-4-(2-hydroxyacetyl)-1H-isochromen-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 220.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 8-hydroxy-4-(2-hydroxyacetyl)-1H-isochromen-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8O5 |
| Molecular Weight | 220.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
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Recommended Standards
- 2-(Carboxymethyl)pyrazolo[1,5-a]pyridine-3-carboxylic Acid (CAS 1446333-71-6)
- 3-(Methoxycarbonyl)pyrazolo[1,5-a]pyridine-2-carboxylic acid (CAS 1476799-51-5)
- 2-Methyl-4-nitro-6-(4H-1,2,4-triazol-4-yl)phenol (CAS 1432437-76-7)
- 2-(1-Methyl-1h-pyrazol-4-yl)-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid (CAS 1490858-72-4)
- 3-{2-[(3,5-Dimethoxybenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1220038-96-9)
- 1-Ethynyl-2-methyl-4-nitrobenzene (CAS 163454-82-8)
- 2-(4-Bromo-3-(difluoromethyl)-6-iodopyridin-2-yl)acetic acid (CAS 1806910-71-3)
- 1,2-Dichloro-4-methyl-3-nitrobenzene (CAS 1803814-86-9)
- 4-(3-Bromophenyl)-2,6-diphenylpyrimidine (CAS 864377-28-6)
- (S)-1-(2-(Dimethylamino)phenyl)ethan-1-ol (CAS 1344934-37-7)
- 6-Chloro-4-hydroxy-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester (CAS 1427195-07-0)
- Methyl 4-bromo-2-(cyanomethyl)benzoate (CAS 1083181-36-5)
- 6-Methyl-1H-indazole (CAS 698-24-8)
- Semaglutide Impurity 151 xTFA (CAS CATO-C4X-2226151)
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