Methyl 2-fluoro-6-iodobenzoate CAS 146014-66-6
| CAS No. | 146014-66-6 |
| Molecular Formula | C8H6FIO2 |
| Molecular Weight | 280.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Methyl 2-fluoro-6-iodobenzoate (CAS 146014-66-6) is a high-purity analytical reference standard with the molecular formula C8H6FIO2 and a molecular weight of 280.03 g/mol.
Based on its molecular formula C8H6FIO2, Methyl 2-fluoro-6-iodobenzoate contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 280.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6FIO2 |
| Molecular Weight | 280.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/I-containing |
Related Methyl Standards
- 4-Fluoro-2-iodo-6-methylbenzoic acid (CAS 1048025-60-0)
- Methyl 4-fluoro-3-iodobenzoate (CAS 1121586-29-5)
- 6-Fluoro-3-iodo-2-methylbenzoic Acid (CAS 1149379-03-2)
- Methyl 5-Fluoro-2-iodobenzoate (CAS 1202897-48-0)
- Methyl 2-fluoro-3-iodobenzoate (CAS 1260830-14-5)
- Methyl 3-fluoro-5-iodobenzoate (CAS 1261478-09-4)
- 2-(3-Fluoro-4-iodophenyl)acetic acid (CAS 1261874-58-1)
- 2-Fluoro-5-iodo-4-methylbenzoic Acid (CAS 1300741-56-3)
Recommended Standards
- 3-Fluoro-6-iodo-2-methylbenzoic acid (CAS 1417190-31-8)
- 4-Fluoro-5-iodo-2-methylbenzoic acid (CAS 1533441-18-7)
- 3-Fluoro-2-iodo-6-methylbenzoic Acid (CAS 1417190-24-9)
- 2-(2-Fluoro-4-iodophenyl)acetic acid (CAS 345963-96-4)
- 2-(Tetrahydropyran-2-yloxy)phenol (CAS 21645-25-0)
- 3-(m-tolyl)-[1,2,4]Triazolo[3,4-b][1,3,4]thiadiazol-6-amine (CAS 629652-21-7)
- 4-Methyl-5-(2-phenylcyclopropyl)-4H-1,2,4-triazole-3-thiol (CAS 869947-52-4)
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- 2-iodo-5-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1227270-15-6)
- 2-Oxo-2-((5-((3-phenylpropyl)thio)-1,3,4-thiadiazol-2-yl)amino)acetic acid (CAS 1158451-21-8)
- 7-(Benzyloxy)quinoline-4-carbonitrile (CAS 1630025-67-0)
- 3,3-Dimethoxy-N'-[2-(1H-1,2,4-triazol-1-yl)ethanimidoyl]propanehydrazide (CAS 338395-51-0)
- 2-Chloro-n-[3-(4-cyclohexylphenyl)-1-phenyl-1h-pyrazol-5-yl]acetamide (CAS 956374-40-6)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
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