2-(Chloromethyl)-5-(trifluoromethyl)thiophene CAS 1462383-18-1
| CAS No. | 1462383-18-1 |
| Molecular Formula | C6H4ClF3S |
| Molecular Weight | 200.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Chloromethyl)-5-(trifluoromethyl)thiophene.
2-(Chloromethyl)-5-(trifluoromethyl)thiophene (CAS 1462383-18-1), molecular formula C6H4ClF3S and molecular weight 200.61 g/mol, is a CATO reference standard with documented purity and traceability.
2-(Chloromethyl)-5-(trifluoromethyl)thiophene (C6H4ClF3S) contains sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Chloromethyl)-5-(trifluoromethyl)thiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF3S |
| Molecular Weight | 200.61 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- ethyl 4-(chloromethyl)pyrimidine-5-carboxylate (CAS 1092281-11-2)
- N-(6-(Chloromethyl)-4-hydroxypyridin-2-yl)acetamide (CAS 1393547-67-5)
- 2-Chloromethyl-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-4-one (CAS 1417917-59-9)
- 3-(Chloromethyl)-4-hydroxy-5-methoxybenzaldehyde (CAS 28276-04-2)
- 3-(Chloromethyl)-4-methoxybenzoic acid (CAS 77670-42-9)
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- Ethyl 2-(chloromethyl)pyrimidine-4-carboxylate (CAS 944899-56-3)
- Ethyl 2-(chloromethyl)pyrimidine-5-carboxylate (CAS 944905-97-9)
Recommended Standards
- 3-Chloro-4-methyl-2-(trifluoromethyl)thiophene (CAS 1349715-51-0)
- 2-(4-Chloro-3-cyclopropyl-1H-pyrazol-1-yl)acetic acid (CAS 1006319-36-3)
- Diethyl (2-chloroethyl)phosphonate (CAS 10419-79-1)
- 5-Chloro-6-(ethylamino)pyridine-3-carboxylic acid (CAS 1019461-54-1)
- 4,6-Diisopropylpyrimidin-5-amine (CAS CATO-C3D-262717)
- (4-Chloro-3-(4-oxopiperidine-1-carbonyl)phenyl)boronic acid (CAS 1704080-21-6)
- 1-(4-Chloro-2-hydroxy-6-methylphenyl)ethanone (CAS 87239-37-0)
- Ethyl 3-iodo-4-(methylamino)benzoate (CAS 1589570-14-8)
- 4-Methoxybenzyl 8-methoxy-2H-chromene-3-carboxylate (CAS 338420-70-5)
- Ethyl 2-bromo-2-(3-fluorophenyl)acetate (CAS 66504-00-5)
- 21H,23H-Porphine, 5,15-bis(4-bromophenyl)-10,20-diphenyl- (CAS 401901-10-8)
- 3-(butan-2-yl)aniline hydrochloride (CAS 2031258-70-3)
- (S)-1-BENZYL-3-METHYLPIPERAZINE (CAS 132871-12-6)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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