(2R,6R)-rel-1-Boc-2,6-dimethyl-4-hydroxypiperidine CAS 146337-39-5

Description

Compared with other compounds in its class, the molecular weight of 229.32 g/mol gives (2R,6R)-rel-1-Boc-2,6-dimethyl-4-hydroxypiperidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2R,6R)-rel-1-Boc-2,6-dimethyl-4-hydroxypiperidine (CAS 146337-39-5), molecular formula C12H23NO3 and molecular weight 229.32 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2R,6R)-rel-1-Boc-2,6-dimethyl-4-hydroxypiperidine (C12H23NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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