O-(tert-Butyldimethylsilyl)-N-Fmoc-L-threonine CAS 146346-82-9
| CAS No. | 146346-82-9 |
| Molecular Formula | C25H33NO5Si |
| Molecular Weight | 455.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including O-(tert-Butyldimethylsilyl)-N-Fmoc-L-threonine.
CATO supplies O-(tert-Butyldimethylsilyl)-N-Fmoc-L-threonine (CAS 146346-82-9), a certified reference material (molecular formula C25H33NO5Si, MW 455.62 g/mol) for analytical method development and quality control.
O-(tert-Butyldimethylsilyl)-N-Fmoc-L-threonine (C25H33NO5Si) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), O-(tert-Butyldimethylsilyl)-N-Fmoc-L-threonine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C25H33NO5Si |
| Molecular Weight | 455.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Recommended Standards
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