4-(Chloromethyl)-6,7-dimethyl-2H-1-benzopyran-2-one CAS 146463-74-3

Purity 97%+In StockPharmaceutical Standards
CAS No.146463-74-3
Molecular FormulaC12H11ClO2
Molecular Weight222.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Chloromethyl)-6,7-dimethyl-2H-1-benzopyran-2-one CAS 146463-74-3 chemical structure

Description

The occurrence of 4-(Chloromethyl)-6,7-dimethyl-2H-1-benzopyran-2-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 4-(Chloromethyl)-6,7-dimethyl-2H-1-benzopyran-2-one (CAS 146463-74-3), a certified reference material (molecular formula C12H11ClO2, MW 222.67 g/mol) for analytical method development and quality control.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-(Chloromethyl)-6,7-dimethyl-2H-1-benzopyran-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4-(Chloromethyl)-6,7-dimethyl-2H-1-benzopyran-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H11ClO2
Molecular Weight222.67 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentCl-containing

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