1-(2,2-Difluoroethanesulfonyl)-4-methylbenzene CAS 146536-56-3

Purity 97%+In StockPharmaceutical Standards
CAS No.146536-56-3
Molecular FormulaC9H10F2O2S
Molecular Weight220.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,2-Difluoroethanesulfonyl)-4-methylbenzene CAS 146536-56-3 chemical structure

Description

The occurrence of 1-(2,2-Difluoroethanesulfonyl)-4-methylbenzene is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-(2,2-Difluoroethanesulfonyl)-4-methylbenzene (CAS 146536-56-3), molecular formula C9H10F2O2S and molecular weight 220.24 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(2,2-Difluoroethanesulfonyl)-4-methylbenzene (C9H10F2O2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(2,2-Difluoroethanesulfonyl)-4-methylbenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC9H10F2O2S
Molecular Weight220.24 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1998
Halogen ContentF-containing
Sulfur Atoms1

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