1-(Piperidin-4-ylmethyl)-4-(trifluoromethyl)piperidine CAS 1466005-46-8
| CAS No. | 1466005-46-8 |
| Molecular Formula | C12H21F3N2 |
| Molecular Weight | 250.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(Piperidin-4-ylmethyl)-4-(trifluoromethyl)piperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-(Piperidin-4-ylmethyl)-4-(trifluoromethyl)piperidine (CAS 1466005-46-8) is a high-purity analytical reference standard with the molecular formula C12H21F3N2 and a molecular weight of 250.30 g/mol.
Owing to a nitrile group, fluorine substitution, 1-(Piperidin-4-ylmethyl)-4-(trifluoromethyl)piperidine is typically white to off-white low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 250.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H21F3N2 |
| Molecular Weight | 250.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Piperidin Standards
- 2-(2-Piperidin-4-ylethoxy)isonicotinic acid (CAS 1706430-06-9)
- 1706438-44-9 6-(2-Piperidin-4-ylethoxy)pyridine-2-carboxylic acid KS-00003SSD (CAS 1706438-44-9)
- 6-(2-Piperidin-4-ylethoxy)nicotinic acid (CAS 1706462-52-3)
- 3-(Piperidin-1-ylsulfonyl)benzonitrile (CAS 1016789-41-5)
- 2-(Piperidin-4-ylthio)benzo[d]thiazole (CAS 380637-96-7)
- Piperidin-1-yl(4,5,6,7-tetrahydrobenzo[b]thiophen-3-yl)methanone (CAS 307540-59-6)
- 3-(Piperidin-4-ylmethyl)-5-(thiophen-2-yl)-1,2,4-oxadiazole (CAS 1707586-05-7)
- 3-(Piperidin-4-ylmethyl)-5-(thiophen-3-yl)-1,2,4-oxadiazole (CAS 1779131-56-4)
Recommended Standards
- N-(2-(Pyridin-2-yl)ethyl)cinnolin-4-amine (CAS 143705-45-7)
- (3AS,8aR)-2-(6-methylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole (CAS 1532531-18-2)
- N-(3-(1H-pyrazol-1-yl)propyl)-6-oxopiperidine-3-carboxamide (CAS 1427695-46-2)
- 2-(4-methylbenzoyl)-1H-indol-3-amine (CAS 1552304-61-6)
- (7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methanol (CAS 313656-57-4)
- 2-(4-Bromo-6-(difluoromethyl)-3-methoxypyridin-2-yl)acetic acid (CAS 1806912-40-2)
- 3-(Fluoromethyl)azetidine-3-carbonitrile (CAS 1258067-08-1)
- (2R,3R)-2-Methyl-3-(4H-1,2,4-triazol-4-yl)chroman-4-one (CAS 810692-82-1)
- N-((1-Isopropyl-1H-pyrazol-4-yl)methyl)-3-methyl-1-propyl-1H-pyrazol-4-amine hydrochloride (CAS 1856080-77-7)
- 4-Hydroxy-2-Methylpyridine (CAS 99968-73-7)
- 1401425-93-1 4-(1-Hydrazinoethyl)pyridine hydrochloride (CAS 1401425-93-1)
- 2-Aminopyrido[2,3-b]pyrazin-3(4H)-one (CAS 190144-15-1)
- Pisolithin B (CAS 13244-78-5)
- [His]1+12-Semaglutide (CAS CATO-C4X-2226178)
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