[5-(3-fluoropyridin-4-yl)-1,3,4-thiadiazol-2-yl]methanamine CAS 1466227-72-4
| CAS No. | 1466227-72-4 |
| Molecular Formula | C8H7FN4S |
| Molecular Weight | 210.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
[5-(3-fluoropyridin-4-yl)-1,3,4-thiadiazol-2-yl]methanamine (C8H7FN4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
[5-(3-fluoropyridin-4-yl)-1,3,4-thiadiazol-2-yl]methanamine (CAS 1466227-72-4) is a high-purity analytical reference standard with the molecular formula C8H7FN4S and a molecular weight of 210.23 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7FN4S |
| Molecular Weight | 210.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related fluoropyridin Standards
- (1-(3-Fluoropyridin-2-yl)piperidin-3-yl)methanol (CAS 1339531-11-1)
- 1-{[(3-fluoropyridin-2-yl)oxy]methyl}cyclopentan-1-amine (CAS 1344288-19-2)
- [4-(3-Fluoropyridin-2-yl)oxan-4-yl]methanamine (CAS 1439896-69-1)
- (3-Fluoropyridin-4-yl)(3-hydroxypyrrolidin-1-yl)methanone (CAS 1479634-87-1)
- Ethyl 3-(3-fluoropyridin-2-yl)-3-oxopropanoate (CAS 1093115-27-5)
- Ethyl 3-(5-fluoropyridin-2-yl)-3-oxopropanoate (CAS 1428207-62-8)
- 1-Ethyl-4-(6-fluoropyridin-2-yl)piperazine (CAS 1251093-50-1)
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Recommended Standards
- Ethyl 2,6-dimethoxybenzoate (CAS 1464-96-6)
- 3,8-Dimethylacenaphthenequinone (CAS 146885-81-6)
- Methyl 1-(3-piperidinyl)-1H-1,2,3-triazole-4-carboxylate (CAS 1461869-00-0)
- Methyl 2-hydroxy-2-(3-(methoxymethyl)phenyl)acetate (CAS 1478077-45-0)
- 5-Chloro-4-nitrothiophene-2-sulfonamide (CAS 61714-46-3)
- 2-chloro-4-[3-(trifluoromethoxy)phenyl]pyridine (CAS 1261856-64-7)
- 2-(Bis(5-methylfuran-2-yl)methyl)benzoic acid (CAS 352540-52-4)
- 3-Chloro-4-hydroxy-5-nitrobenzenesulfonic acid (CAS 83732-61-0)
- (2-Bromophenyl)(4-chloro-3-methylphenyl)methanol (CAS 1443345-22-9)
- Salbutamol Impurity 90 (CAS CATO-C4X-117690)
- [(3R)-1-Methylpiperidin-3-yl]methanamine (CAS 1217627-70-7)
- 2',5'-Dimethyl-[1,1'-biphenyl]-3-ol (CAS 1177232-47-1)
- (E)-icos-3-ene (CAS 74685-33-9)
- Semaglutide Impurity 176 (CAS CATO-C4X-2226176)
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