5-Azaspiro[2.3]hexane, trifluoroacetic acid CAS 1466514-80-6
| CAS No. | 1466514-80-6 |
| Molecular Formula | C2HF3O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 197.16 g/mol gives 5-Azaspiro[2.3]hexane, trifluoroacetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Azaspiro[2.3]hexane, trifluoroacetic acid (CAS 1466514-80-6), molecular formula C2HF3O2C5H9N and molecular weight 197.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Azaspiro[2.3]hexane, trifluoroacetic acid (C2HF3O2C5H9N) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C2HF3O2 C5H9N |
| Molecular Weight | 197.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Azaspiro Standards
- 2-Azaspiro[4.4]Nonan-1-one (CAS 1004-51-9)
- 2-Azaspiro[4.5]decan-1-one (CAS 1005-85-2)
- 2-(3-Azaspiro[5.5]Undecan-3-yl)ethan-1-amine (CAS 1012-58-4)
- 1-Oxa-2-azaspiro[4.5]dec-2-ene-3-carboxylicacid (CAS 1015770-72-5)
- Methyl 2-{3-azaspiro[5.5]undecan-9-yl}acetate hydrochloride (CAS 1017540-91-8)
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- Benzyl 6-azaspiro[2.5]octane-6-carboxylate (CAS 1037834-61-9)
Recommended Standards
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- 4-Methoxy-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine (CAS 1200132-24-6)
- 5-(4-Fluorophenyl)pentan-1-amine (CAS 1216003-55-2)
- (2S,5S)-2,5-Diethylpiperazine (CAS 1240590-22-0)
- 5-bromo-3-ethyl-6-methylpyridin-2-amine (CAS 1098652-28-8)
- 4-Amino-6-((6-fluoro-1H-indol-5-yl)oxy)pyrimidine-5-carbaldehyde (CAS 919485-94-2)
- Methyl 2-(acryloyloxy)benzoate (CAS 4513-46-6)
- N-(3-Methoxyphenyl)-4-(methylthio)benzo[d]thiazol-2-amine (CAS 890960-47-1)
- Peptide YY (3-36) (human) (CAS 123583-37-9)
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