2-(Chloromethyl)-5-phenylpyridine CAS 146775-28-2
| CAS No. | 146775-28-2 |
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Chloromethyl)-5-phenylpyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(Chloromethyl)-5-phenylpyridine (CAS 146775-28-2) is a high-purity analytical reference standard with the molecular formula C12H10ClN and a molecular weight of 203.67 g/mol.
The molecular framework of 2-(Chloromethyl)-5-phenylpyridine (C12H10ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Chloromethyl)-5-phenylpyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClN |
| Molecular Weight | 203.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
- 2-(4-(Chloromethyl)phenyl)pyridine (CAS 147936-70-7)
- 2-(Chloromethyl)-6-phenylpyridine (CAS 147937-33-5)
- 2-(Chloromethyl)-4-phenylpyridine (CAS 147937-34-6)
- 4-(Chloromethyl)-2-phenylpyridine (CAS 147937-35-7)
- 3-(Chloromethyl)-5-phenylpyridine (CAS 177976-31-7)
- 5-(Chloromethyl)-2-phenylpyridine (CAS 5229-40-3)
- 4-(Chloromethyl)-2-(oxolan-2-yl)-1,3-thiazole (CAS 1423028-25-4)
- 4-(3-(Chloromethyl)-1,2,4-oxadiazol-5-yl)morpholine (CAS 1393558-45-6)
Recommended Standards
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- 1-Chloro-4-cyclopropylisoquinoline (CAS 1409964-40-4)
- Scandioside Methyl Ester (CAS 27530-67-2)
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- 1-((4-Methylmorpholin-2-yl)methyl)-1h-pyrazol-4-amine (CAS 1503705-38-1)
- 2-(4-Bromophenyl)-4,4,6-trimethyl-1,3-dioxane (CAS 171367-53-6)
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