1,4-Bis((2-chloro-4-methoxyphenoxy)methyl)benzene CAS 146949-20-4
| CAS No. | 146949-20-4 |
| Molecular Formula | C22H20Cl2O4 |
| Molecular Weight | 419.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,4-Bis((2-chloro-4-methoxyphenoxy)methyl)benzene is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 1,4-Bis((2-chloro-4-methoxyphenoxy)methyl)benzene (CAS 146949-20-4), a certified reference material (molecular formula C22H20Cl2O4, MW 419.30 g/mol) for analytical method development and quality control.
1,4-Bis((2-chloro-4-methoxyphenoxy)methyl)benzene (C22H20Cl2O4) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,4-Bis((2-chloro-4-methoxyphenoxy)methyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H20Cl2O4 |
| Molecular Weight | 419.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 2-(2-Iodoquinolin-3-yl)-5,7-dimethyl-1,3-diazaadamantane (CAS 1442482-43-0)
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- Methyl N-(2,4-dimethoxyphenyl)-N-[(4-methylphenyl)sulfonyl]glycinate (CAS 425608-33-9)
- 2-(5-Methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)propanehydrazide (CAS 1005592-15-3)
- 61704-30-1 6-(4-Chlorophenyl)pyridine-2-carbaldehyde DTXSID90494575 (CAS 61704-30-1)
- 5-(4-Ethylphenyl)isoxazol-3-amine (CAS 1268076-96-5)
- 4-(Chloromethyl)-1-ethyl-1H-pyrazole hydrochloride (CAS 1332529-52-8)
- 3-Isopropyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine (CAS 376587-12-1)
- Methyl 4-((tert-butyldimethylsilyl)oxy)-2-hydroxybutanoate (CAS 847199-27-3)
- 3-(6-Methyl-1,2,3,4-tetrahydroquinolin-1-yl)butan-2-one (CAS 1152866-99-3)
- (2S,4R)-1-((9H-Fluoren-9-yl)methyl) 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate (CAS 122350-59-8)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
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