2'-F-dUPhosphoramidite CAS 146954-75-8
| CAS No. | 146954-75-8 |
| Molecular Formula | C39H46FN4O8P |
| Molecular Weight | 748.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2'-F-dUPhosphoramidite.
CATO supplies 2'-F-dUPhosphoramidite (CAS 146954-75-8), a certified reference material (molecular formula C39H46FN4O8P, MW 748.78 g/mol) for analytical method development and quality control.
2'-F-dUPhosphoramidite (C39H46FN4O8P) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2'-F-dUPhosphoramidite under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C39H46FN4O8P |
| Molecular Weight | 748.78 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Recommended Standards
- (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite (CAS 142246-63-7)
- Ceftizoxime Dimer Impurity 38 (CAS CATO-C4X-179338)
- 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite (CAS 1190089-70-3)
- Methyl 2,3,4-tri-O-benzoyl-6-O-trityl-a-D-galactopyranoside (CAS 130163-39-2)
- 3-(Piperazin-1-yl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one hydrochloride (CAS 1047976-56-6)
- 6-Methyl-1,5-naphthyridin-2-ol (CAS 764717-60-4)
- (2-Chloro-1,3-thiazol-5-yl)methyl N-(3,4-dichlorophenyl)carbamate (CAS 341967-59-7)
- 3-(2-(4-Bromophenoxy)acetamido)propanoic acid (CAS 446828-74-6)
- 6921-28-4 TST5UMI4J4 Dipropargylamine Di-2-propynylamine 2-Propyn-1-amine, N-2-propynyl- (9CI) 4-04-00-01137 (Beilstein Handbook Reference) BRN 1735854 EINECS 230-036-4 NSC 80652 N-2-Propynyl-2-propyn-1-amine UNII-TST5UMI4J4 (CAS 6921-28-4)
- Ledipasvir (CAS 1256388-51-8)
- D,L-threo-β-Hydroxy Aspartic Acid (CAS 4294-45-5)
- (3-Chlorophenyl)(3-(4-chlorophenyl)-5,6-dihydropyridazin-1(4H)-yl)methanone (CAS 159799-55-0)
- 2-Fluoro-5-(trifluoromethyl)phenol (CAS 141483-15-0)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com