Ethyl 2-(3-bromo-5-methylthiophen-2-yl)-2-oxoacetate CAS 1470541-73-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1470541-73-1
Molecular FormulaC9H9BrO3S
Molecular Weight277.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Ethyl 2-(3-bromo-5-methylthiophen-2-yl)-2-oxoacetate CAS 1470541-73-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 277.13 g/mol gives Ethyl 2-(3-bromo-5-methylthiophen-2-yl)-2-oxoacetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ethyl 2-(3-bromo-5-methylthiophen-2-yl)-2-oxoacetate (CAS 1470541-73-1) is a high-purity analytical reference standard with the molecular formula C9H9BrO3S and a molecular weight of 277.13 g/mol.

The molecular framework of Ethyl 2-(3-bromo-5-methylthiophen-2-yl)-2-oxoacetate (C9H9BrO3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Ethyl 2-(3-bromo-5-methylthiophen-2-yl)-2-oxoacetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H9BrO3S
Molecular Weight277.13 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentBr-containing
Sulfur Atoms1

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