2-Bromo-4-(4-chloro-phenyl)-nicotinic acid methyl ester CAS 147078-80-6
| CAS No. | 147078-80-6 |
| Molecular Formula | C13H9BrClNO2 |
| Molecular Weight | 326.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 326.57 g/mol gives 2-Bromo-4-(4-chloro-phenyl)-nicotinic acid methyl ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-Bromo-4-(4-chloro-phenyl)-nicotinic acid methyl ester (CAS 147078-80-6), a certified reference material (molecular formula C13H9BrClNO2, MW 326.57 g/mol) for analytical method development and quality control.
The molecular framework of 2-Bromo-4-(4-chloro-phenyl)-nicotinic acid methyl ester (C13H9BrClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Bromo-4-(4-chloro-phenyl)-nicotinic acid methyl ester meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9BrClNO2 |
| Molecular Weight | 326.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-2-chloro-N-(2-hydroxyphenyl)benzamide (CAS 1009975-56-7)
- Benzyl 5-bromo-2-chloroisonicotinate (CAS 1881980-41-1)
- 5-Bromo-4'-chlorosalicylanilide (CAS 3679-64-9)
- Benzyl 3-bromo-2-chloroisonicotinate (CAS 2379321-79-4)
- 6-Bromo-3-oxo-3,4-dihydro-2h-1,4-benzoxazine-7-sulfonyl chloride (CAS 1050884-93-9)
- 4-Bromo-2-(2-chloro-6-fluorophenyl)-3H-imidazo[4,5-c]pyridine (CAS 1334411-85-6)
- 5-bromo-4-acetamido-2-methylbenzene-1-sulfonyl chloride (CAS 1432680-21-1)
- 2-(3-Bromo-2-chloro-6-fluorophenyl)-1H-imidazo[4,5-c]pyridine (CAS 1439824-02-8)
Recommended Standards
- 5-(2-Chloropyridin-4-yl)-3-(2,4-dichlorophenyl)-1,2,4-oxadiazole (CAS 1119396-33-6)
- 5-(2-Chloropyridin-4-yl)-3-(3,5-dichlorophenyl)-1,2,4-oxadiazole (CAS 1707727-37-4)
- 5-(6-Chloropyridin-3-yl)-3-(2,4-dichlorophenyl)-1,2,4-oxadiazole (CAS 1119396-12-1)
- 5-(2-Chloropyridin-4-yl)-3-(2,5-dichlorophenyl)-1,2,4-oxadiazole (CAS 1708400-93-4)
- 4-(((1-Methyl-1H-pyrazol-5-yl)methyl)amino)cyclohexan-1-ol (CAS 1156713-74-4)
- 6,6',6",6"'-(9H-Carbazole-1,3,6,8-tetrayl)tetrakis(2-naphthoic acid) (CAS 2275759-34-5)
- 2,4-Dinitrobenzaldehyde oxime (CAS 3236-33-7)
- 1,2-Dimethoxyethane (CAS 110-71-4)
- 4,7-dichloro-8-fluoro-pyrido[4,3-d]pyrimidine (CAS 2454396-94-0)
- (+)-Catechinhydrate (CAS 225937-10-0)
- 4-Chloro-N,N-diethylpyrimidin-2-amine (CAS 71406-62-7)
- TERT-BUTYL 4-(3-NITRO-1H-PYRAZOL-1-YL)PIPERIDINE-1-CARBOXYLATE (CAS 1201935-68-3)
- 4,6,8-Trimethylquinolin-2-amine (CAS 1307239-65-1)
- Anti-Inflammatory Peptide 1 (CAS 118850-71-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com