Alcaftadine Impurity 1 CAS 147083-93-0
| CAS No. | 147083-93-0 |
| Molecular Formula | C19H21N3O2 |
| Molecular Weight | 323.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Alcaftadine Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Alcaftadine Impurity 1 (CAS 147083-93-0) is a certified pharmaceutical impurity reference standard with the molecular formula C19H21N3O2 and a molecular weight of 323.39 g/mol.
Alcaftadine Impurity 1 (C19H21N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H21N3O2 |
| Molecular Weight | 323.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 3 |
Related Alcaftadine Standards
Recommended Standards
- Indobufen Impurity 11 (CAS 36691-02-8)
- Olopatadine Impurity 9 (CAS 113835-92-0)
- Ripasudil (CAS 223645-67-8)
- Olotadine lmpurity 55 (CAS CATO-C4X-171855)
- Esmolol Impurity 49 (CAS CATO-C4X-189149)
- Mirogabalin Impurity 160 (CAS CATO-C4X-2924160)
- Cefotiam Impurity 41 (CAS 61607-68-9)
- N‐Nitrosonorfloxacin (CAS 74011-53-3)
- N,N,2'-Trimethyl[1,1'-biphenyl]-4-amine (CAS 273937-86-3)
- 1-(3-Bromo-7-chloro-2-methylpyrazolo[1,5-a]pyrimidin-5-yl)cyclopropan-1-ol (CAS 2387601-18-3)
- 1,4-Dioxaspiro[4.5]decan-7-amine (CAS 49672-69-7)
- 6-Methyl-2-(pyridin-3-yl)quinoline-4-carbonyl chloride (CAS 1203205-47-3)
- 5-Bromo-2-hydroxy-3-methylbenzyl alcohol (CAS 77691-33-9)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com