Methyl 3-amino-6-chloro-5-(hexylamino)pyrazine-2-carboxylate CAS 1472-27-1
| CAS No. | 1472-27-1 |
| Molecular Formula | C12H19ClN4O2 |
| Molecular Weight | 286.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3-amino-6-chloro-5-(hexylamino)pyrazine-2-carboxylate.
Methyl 3-amino-6-chloro-5-(hexylamino)pyrazine-2-carboxylate (CAS 1472-27-1) is a high-purity analytical reference standard with the molecular formula C12H19ClN4O2 and a molecular weight of 286.76 g/mol.
Based on its molecular formula C12H19ClN4O2, Methyl 3-amino-6-chloro-5-(hexylamino)pyrazine-2-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.76 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H19ClN4O2 |
| Molecular Weight | 286.76 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Methyl Standards
- 2-(5-Amino-2-chlorophenyl)-N,N-dimethyl-1H-benzo[d]imidazol-5-amine (CAS 1079264-85-9)
- 6-amino-1-[(4-chlorophenyl)methyl]-1,2,3,4-tetrahydroquinolin-2-one (CAS 1153515-25-3)
- 3-Amino-1-benzyl-4-(2-chlorophenyl)azetidin-2-one (CAS 1291488-55-5)
- (S)-2-Amino-N-(2-chloro-6-fluorobenzyl)-N-ethyl-3-methylbutanamide (CAS 1354015-69-2)
- 3-Amino-4-chloro-N-(2-furylmethyl)-benzenesulfonamide (CAS 1036545-43-3)
- 3-Amino-2-((4-chlorophenyl)amino)quinazolin-4(3H)-one (CAS 95241-44-4)
- 6-Amino-4-(4-chlorophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 89607-39-6)
- 3-Amino-N-(4-chlorophenyl)benzofuran-2-carboxamide (CAS 609805-00-7)
Recommended Standards
- 1-(4-Butylphenyl)-4-chloro-1H-pyrazolo[3,4-d]pyrimidine (CAS 1416339-54-2)
- 4-Chloro-2-cyclohexylbenzofuro[3,2-d]pyrimidine (CAS 1706459-73-5)
- 5-(3-(Tert-butyl)-5-chloro-4h-1,2,4-triazol-4-yl)quinoline (CAS 1354963-43-1)
- (E)-2-(3-((3-chloro-2-methylphenyl)amino)-1-(dimethylamino)allylidene)malononitrile (CAS 339101-96-1)
- 2-Ethoxypyrimidine-4-carboxylic acid (CAS 1312556-74-3)
- 3-chloro-4-hydrazinylbenzenesulfonamide hydrochloride (CAS CATO-C3D-262505)
- Octan-2-amine hydrochloride (CAS 24301-94-8)
- (6-Chloropyridin-3-yl)(piperazin-1-yl)methanone (CAS 1240566-37-3)
- N-(3-Fluorobenzyl)formamide (CAS 180207-86-7)
- 4-(2-Bromophenethyl)morpholine (CAS 736991-23-4)
- 1-Methyl-4-nitro-1H-pyrrole-2-carbonyl chloride (CAS 28494-51-1)
- tert-Butyl N-[5-(trifluoromethyl)pyridin-3-yl]carbamate (CAS 1187055-61-3)
- 4-(2-Chloro-4-methoxyphenyl)-5-methyl-1H-pyrazol-3-amine (CAS 817636-89-8)
- Des-Ile17-Tirzepatide (CAS CATO-CPTD788956)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com