3-Amino-2-(4-methylpiperazin-1-yl)isonicotinic acid CAS 1472024-01-3
| CAS No. | 1472024-01-3 |
| Molecular Formula | C11H16N4O2 |
| Molecular Weight | 236.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Amino-2-(4-methylpiperazin-1-yl)isonicotinic acid (CAS 1472024-01-3), a certified reference material (molecular formula C11H16N4O2, MW 236.27 g/mol) for analytical method development and quality control.
3-Amino-2-(4-methylpiperazin-1-yl)isonicotinic acid (C11H16N4O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16N4O2 |
| Molecular Weight | 236.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 4 |
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- 4,5-Dichloro-2-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)pyridazin-3(2h)-one (CAS 1061384-31-3)
- Solifenacin Impurity 30 (CAS 34583-34-1)
- Ethyl 4-formyl-1-methyl-1H-imidazole-5-carboxylate (CAS 2111324-86-6)
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