1-(2,4-Dihydroxyphenyl)-2-fluoroethanone CAS 147220-82-4
| CAS No. | 147220-82-4 |
| Molecular Formula | C8H7FO3 |
| Molecular Weight | 170.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 170.14 g/mol gives 1-(2,4-Dihydroxyphenyl)-2-fluoroethanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(2,4-Dihydroxyphenyl)-2-fluoroethanone (CAS 147220-82-4), molecular formula C8H7FO3 and molecular weight 170.14 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2,4-Dihydroxyphenyl)-2-fluoroethanone (C8H7FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7FO3 |
| Molecular Weight | 170.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Dihydroxyphenyl Standards
- 1-(3,4-Dihydroxyphenyl)-2-fluoroethanone (CAS 402-99-3)
- 2-(2,6-Dihydroxyphenyl)acetic acid (CAS 64700-73-8)
- 1-(2,4-Dihydroxyphenyl)ethan-1-one oxime (CAS 6134-79-8)
- N-(2,4-dihydroxyphenyl)acetamide (CAS 71516-07-9)
- N-(2,5-Dihydroxyphenyl)acetamide (CAS 93525-28-1)
- (E)-1-(2,6-Dihydroxyphenyl)ethanone oxime 22233-82-5 C8H9NO3 V4466 (CAS 22233-82-5)
- 2-(3,4-Dihydroxyphenyl)acetimidamide (CAS 87112-04-7)
- 1-(3,5-Dihydroxyphenyl)propan-2-one (CAS 15580-07-1)
Recommended Standards
- Methyl 6-amino-4-fluoropicolinate (CAS 1446509-55-2)
- 4-Fluoro-2-methyl-6-nitroaniline (CAS 147285-87-8)
- Methyl 6-amino-3-fluoropicolinate (CAS 1446509-50-7)
- 4-Fluoro-3-methyl-2-nitroanilin (CAS 147285-88-9)
- 1-(3-Fluoropyridin-2-yl)-2,2-dimethylpropan-1-ol (CAS 1499091-66-5)
- 3-(4-Chlorobenzyl)-1,3,8-triazaspiro[4.5]Decane-2,4-dione (CAS 1092277-60-5)
- 5-(Morpholinosulfonyl)thiophene-2-sulfonyl chloride (CAS 1306605-71-9)
- 2,4,6-Trimethyl-N-(4-oxocyclohexyl)-N-propyl-benzenesulfonamide (CAS 1026083-70-4)
- Methyl 2-(1-ethyl-3-methyl-1h-pyrazol-4-yl)quinoline-4-carboxylate (CAS 1004644-10-3)
- 2-Amino-5-(2,5-dichlorophenyl)isonicotinic acid (CAS 1261945-05-4)
- 1-(Chroman-2-yl)-N-((5-(4-fluorophenyl)pyridin-3-yl)methyl)methanamine (CAS 177975-08-5)
- 4-(4-Bromo-1H-pyrrole-2-carbonyl)thiomorpholine (CAS 923200-04-8)
- (E)-1,4-dimethoxy-2-(2-nitrovinyl)benzene 1,4-Dimethoxy-2-(2-nitroethenyl) benzene 40276-11-7 (CAS 40276-11-7)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com